UCC-SMART

Utrecht Cardiovascular Cohorts – Second Manifestations of Arterial Disease...

Description

The UCC-SMART Study is a single-centre prospective cohort study, ongoing in both inclusion and follow-up, in which patient care and scientific research concerning cardiovascular risk factors and disease are integrated....

General Design

Cohort type

Clinical cohort, Biobank

Design

Longitudinal

Design description

Single-centre prospective cohort study, ongoing in both baseline and follow-up. The baseline screening programme consists of questionnaires, physical examination, an ECG, blood, urine and radiology testing. Except for the questionnaires, to be filled out before the hospital visit, the diagnostic components of the programme take place during a 1-day visit. For follow-up patients receive annual questionnaires with questions on hospital admissions and outpatient clinic visits, regardless of whether they are still under the care of the UMC Utrecht.

Design schematic
Design schematic
Collection type

Prospective

Start/End year

1996 - ongoing

Population

Countries

Netherlands (the)

Regions

Limburg, Zeeland, Zuid-Holland, Noord-Holland, Noord-Brabant, Flevoland, Utrecht, Gelderland, Overijssel, Drenthe, Friesland, Groningen

Number of participants

15500

Number of participants with samples

15000

Population age groups

Adult (18+ years)

Main medical condition
  • IX Diseases of the circulatory system
  • XV Pregnancy, childbirth and the puerperium
  • IV Endocrine, nutritional and metabolic diseases
  • VII Diseases of the eye and adnexa
Inclusion criteria
  • Age group inclusion criterion
  • Age of majority inclusion criterion
  • Defined population inclusion criterion
  • Family status inclusion criterion
  • Health status inclusion criterion
  • Hospital patient inclusion criterion
Other inclusion criteria

Not pregnant, no short life expectancy and sufficiently fluent in Dutch.

Contributors

  • UCC-SMART Study GroupUCC-SMART@umcutrecht.nl

    The UCC-SMART Study Group directs the academic focus of research using the UCC-SMART data and consists of staff members from both epidemiological and clinical departments.

Available Data & Samples

Data categories

  • Biological samples
  • Survey data
  • Imaging data
  • Physiological/Biochemical measurements
  • Omics

Sample categories

  • Serum
  • Blood
  • Urine
  • Plasma
  • DNA
  • Saliva

Areas of information

  • Socio-demographic and economic characteristics
  • Non-pharmacological interventions
  • Lifestyle and behaviours
  • Birth, pregnancy and reproductive health history
  • Perception of health, quality of life, development and functional limitations
  • Symptoms and signs
  • Medication and supplements
  • Health and community care services utilization
  • Physical measures and assessments
  • Laboratory measures
  • Death
  • Cognition, personality and psychological measures and assessments

Subpopulations

List of subcohorts or subpopulations for this resource...

Collection events

List of collection events defined for this resource...

Networks

List of networks in which this cohort is involved...

Access conditions

The UCC-SMART Study group directs the academic focus of research using the UCC-SMART data and consists of staff members from both epidemiological and clinical departments. All data presented in this manuscript will be available upon reasonable reques...

Data access conditions

disease specific research

Data use conditions
  • collaboration required
  • project specific restriction
  • return to database or resource
Release type
  • Annually
Release description

Yearly update of new inclusions and follow-up events.

Linkage options

GBA, CBS, SFK, RENINE, LBZ, Regionale ambulance diensten, Vektis and other regional and national registries

Funding & Acknowledgements

Funding

The UCC-SMART Study was financially supported by the UMC Utrecht, the Netherlands.

Acknowledgements

We gratefully acknowledge the contribution of the participants, the research nurses, RBvP (data manager), AV (study manager), the founders of the SMART Study in 1996: A Algra, J D Banga, B C Eikelboom and Y van der Graaf, and the members of the UCC-SMART Study group: MJMC, HMN and MGvdM (co-PI), Department of Cardiology; GJdB and MT (co-PI), Department of Vascular Surgery; MLB and MvS, Julius Center for Health Sciences and Primary Care; MHE-V, Department of Geriatrics; PAdJ, Department of Radiology; ATL, Department of Gynaecology and Obstetrics; NPvdK, Department of Cardiothoracic Surgery; LJK and YMR, Department of Neurology; MCV, Department of Nephrology and Hypertension; JAND (co-PI) and FLJV (PI), Department of Vascular Medicine, UMC Utrecht